Phoenix rds automated diffusion system
The Phoenix RDS Robotic Diffusion Station refines the art of diffusion testing by incorporating Teledyne Hanson’s breakthroughs in four areas: diffusion cell design; heating and stirring; automated sampling and collection; and computerized control. The dry heat diffusion cell at the heart of the system delivers significantly improved test results as compared to traditional water-jacketed, displacement-sampling systems. The precision heating and stirring components built into each of the six-cell blocks provide outstanding control of temperature and speed. Automatic sampling and collection are accomplished through a syringe driven probe on an XYZ platform controlled by Teledyne Hanson’s sophisticated Diffusion Master software. The automated system mimics the way sampling, collection, and media replace are performed by laboratory analysts when working manually, while simultaneously reducing the potential for variances due to procedural inconsistencies. The modular design of the six-cell dry-heat block allows laboratories to move smoothly between manual and automated methods when scaling to higher numbers of experiments.
Dissolution testing determines the release rate of an active pharmaceutical ingredient in
tablet or capsule form as it dissolves into solution.
Diffusion testing is a release rate test of an active pharmaceutical ingredient in semisolid form as it permeates through a skin-like membrane into solution.
Physical testing refers to the monitoring of physical characteristics of a drug product,
typically oral dosage forms such as tablets and capsules.